Cellular senescence is a phenomenon characterized by the cessation of cell division. In their experiments during the early 1960s, Leonard Hayflick and Paul Moorhead found that normal human fetal fibroblasts in culture reach a maximum of approximately 50 cell population doublings before becoming senescent. This process called the Hayflick limit is also known as \"replicative senescence\", since it is brought about through replication. Hayflick's discovery of mortal cells paved the path for the discovery and understanding of cellular aging molecular pathways. Cellular senescence can be initiated by a wide variety of stress inducing factors. These stress factors include both environmental and internal damaging events, abnormal cellular growth, oxidative stress, autophagy factors, among many other things.
"}{"type":"standard","title":"Warner Bros. Pictures","displaytitle":"Warner Bros. Pictures","namespace":{"id":0,"text":""},"wikibase_item":"Q8016302","titles":{"canonical":"Warner_Bros._Pictures","normalized":"Warner Bros. Pictures","display":"Warner Bros. Pictures"},"pageid":61086090,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/0/0c/Warner_Bros._Pictures_2023_%28Alt%29.svg/330px-Warner_Bros._Pictures_2023_%28Alt%29.svg.png","width":320,"height":294},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/0/0c/Warner_Bros._Pictures_2023_%28Alt%29.svg/1272px-Warner_Bros._Pictures_2023_%28Alt%29.svg.png","width":1272,"height":1168},"lang":"en","dir":"ltr","revision":"1286113976","tid":"704f42c8-1bcc-11f0-9b4a-950c56f1a898","timestamp":"2025-04-17T20:42:12Z","description":"American film studio","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Warner_Bros._Pictures","revisions":"https://en.wikipedia.org/wiki/Warner_Bros._Pictures?action=history","edit":"https://en.wikipedia.org/wiki/Warner_Bros._Pictures?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Warner_Bros._Pictures"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Warner_Bros._Pictures","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Warner_Bros._Pictures","edit":"https://en.m.wikipedia.org/wiki/Warner_Bros._Pictures?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Warner_Bros._Pictures"}},"extract":"Warner Bros. Pictures is an American film studio and distribution arm of the Warner Bros. Motion Picture Group division of Warner Bros., both of which are owned by Warner Bros. Discovery. It is headquartered at the Warner Bros. Studios complex in Burbank, California. Animated films produced by Warner Bros. Pictures Animation are also released under the studio banner.","extract_html":"
Warner Bros. Pictures is an American film studio and distribution arm of the Warner Bros. Motion Picture Group division of Warner Bros., both of which are owned by Warner Bros. Discovery. It is headquartered at the Warner Bros. Studios complex in Burbank, California. Animated films produced by Warner Bros. Pictures Animation are also released under the studio banner.
"}{"type":"standard","title":"Robert Lucius West","displaytitle":"Robert Lucius West","namespace":{"id":0,"text":""},"wikibase_item":"Q91315373","titles":{"canonical":"Robert_Lucius_West","normalized":"Robert Lucius West","display":"Robert Lucius West"},"pageid":72336527,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/4/4f/Robert_Lucius_West%2C_self_portrait.png","width":250,"height":306},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/4/4f/Robert_Lucius_West%2C_self_portrait.png","width":250,"height":306},"lang":"en","dir":"ltr","revision":"1262247158","tid":"3c2fa75e-b6ee-11ef-b5f4-ae41e4a9ffad","timestamp":"2024-12-10T11:59:40Z","description":"Irish artist","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Robert_Lucius_West","revisions":"https://en.wikipedia.org/wiki/Robert_Lucius_West?action=history","edit":"https://en.wikipedia.org/wiki/Robert_Lucius_West?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Robert_Lucius_West"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Robert_Lucius_West","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Robert_Lucius_West","edit":"https://en.m.wikipedia.org/wiki/Robert_Lucius_West?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Robert_Lucius_West"}},"extract":"Robert Lucius West was an Irish artist, draughtsman and teacher.","extract_html":"
Robert Lucius West was an Irish artist, draughtsman and teacher.
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